RTA is a disorder of the renal tubules that leads to a nonanion gap hyperchlore mic metabolic acidosis. antabuse Although endoscopy is ini tially more expensive its use reduces the number of patients treated inappropriately.THE RISE OF SCIENTIFIC MEDICINE The Microscope Revolution ERMS SUCH AS BACTERIA AND VIRUSES germ cells including eggs and sperm tiny parasites such as malarias plasmodium and the smallest blood vessels known as capillaries all these are invisible to the naked eye and were unknown before the invention of the light microscope in the late th century.